Oleh karena itu, ovarium merupakan bagian pertama dalam rongga pelvis yang dikenai endometriosis. Fragmen endometrial tersebut dilemparkan dari infundibulum tuba falopii menuju ke ovarium yang akan menjadi tempat tumbuhnya. Jaringan endometirum yang tumbuh di luar uterus, terdiri dari fragmen endometrial. The diagnostic potential of NGAL and MMP-9 in differentiating high-stage (FIGO III and IV) and low-stage (FIGO I and II) cancer and predicting the cell differentiation grade (G1 versus G3) on the basis of the analyses of AUC values was determined to be 0.91 and 0.79 for NGAL and 0.82 and 0.84 for MMP-9, respectively.
The AUC values for NGAL and MMP-9 were 0.9 and 0.78, respectively. Lipocalin-2/NGAL and MMP-9 concentrations were quantified in serum by multiplex fluorescent bead-based immunoassays (Luminex Corporation, Austin, TX, USA).
Abstract The objectives of the study were to assess the relationship between the serum levels of MMP-9 and NGAL and the clinical staging and histopathological grade of the tumor.